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Abstract The cooling strength of the Urca pair,63Fe–63Mn, exhibits an extensive range of variation due to the uncertainty in the spin parity of the ground state of63Fe. To investigate the cooling effect of this Urca pair on the thermal evolution of neutron star crusts, we performed simulations on neutron star structure and evolution under various spin-parity assignment scenarios. When adopting recently evaluated nuclear data,63Fe–63Mn emerges as one of the strongest Urca pairs. In the case of MAXI J0556-332,63Fe–63Mn is the only pair above the shallow heating layer, significantly impacting the cooling curve and the superburst ignition. Moreover, the constraint on the past nucleosynthesis reduced to one-quarter of its original value, falling within three decades, which enables the validation of nuclear reaction theories in the outer layers of neutron stars. Our results highlight the need for more precise measurements of theβ−decay of63Mn to better determine the Urca cooling effect of the63Fe–63Mn pair in accreted neutron star crusts.more » « lessFree, publicly-accessible full text available August 22, 2026
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Distributed energy resources (DERs) are gaining prominence due to their advantages in improving energy efficiency, reducing carbon emissions, and enhancing grid resilience. Despite the increasing deployment, the potential of DERs has yet to be fully explored and exploited. A fundamental question restrains the management of numerous DERs in large-scale power systems, “How should DER data be securely processed and DER operations be efficiently optimized?” To address this question, this paper considers two critical issues, namely privacy for processing DER data and scalability in optimizing DER operations, then surveys existing and emerging solutions from a multi-agent framework perspective. In the context of scalability, this paper reviews state-of-the-art research that relies on parallel control, optimization, and learning within distributed and/or decentralized information exchange structures, while in the context of privacy, it identifies privacy preservation measures that can be synthesized into the aforementioned scalable structures. Despite research advances in these areas, challenges remain because these highly interdisciplinary studies blend a wide variety of scalable computing architectures and privacy preservation techniques from different fields, making them difficult to adapt in practice. To mitigate this issue, this paper provides a holistic review of trending strategies that orchestrate privacy and scalability for large-scale power system operations from a multi-agent perspective, particularly for DER control problems. Furthermore, this review extrapolates new approaches for future scalable, privacy-aware, and cybersecure pathways to unlock the full potential of DERs through controlling, optimizing, and learning generic multi-agent-based cyber–physical systems.more » « lessFree, publicly-accessible full text available March 6, 2026
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Free, publicly-accessible full text available November 1, 2026
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People with blindness and low vision (pBLV) encounter substantial challenges when it comes to comprehensive scene recognition and precise object identification in unfamiliar environments. Additionally, due to the vision loss, pBLV have difficulty in accessing and identifying potential tripping hazards independently. Previous assistive technologies for the visually impaired often struggle in real-world scenarios due to the need for constant training and lack of robustness, which limits their effectiveness, especially in dynamic and unfamiliar environments, where accurate and efficient perception is crucial. Therefore, we frame our research question in this paper as: How can we assist pBLV in recognizing scenes, identifying objects, and detecting potential tripping hazards in unfamiliar environments, where existing assistive technologies often falter due to their lack of robustness? We hypothesize that by leveraging large pretrained foundation models and prompt engineering, we can create a system that effectively addresses the challenges faced by pBLV in unfamiliar environments. Motivated by the prevalence of large pretrained foundation models, particularly in assistive robotics applications, due to their accurate perception and robust contextual understanding in real-world scenarios induced by extensive pretraining, we present a pioneering approach that leverages foundation models to enhance visual perception for pBLV, offering detailed and comprehensive descriptions of the surrounding environment and providing warnings about potential risks. Specifically, our method begins by leveraging a large-image tagging model (i.e., Recognize Anything Model (RAM)) to identify all common objects present in the captured images. The recognition results and user query are then integrated into a prompt, tailored specifically for pBLV, using prompt engineering. By combining the prompt and input image, a vision-language foundation model (i.e., InstructBLIP) generates detailed and comprehensive descriptions of the environment and identifies potential risks in the environment by analyzing environmental objects and scenic landmarks, relevant to the prompt. We evaluate our approach through experiments conducted on both indoor and outdoor datasets. Our results demonstrate that our method can recognize objects accurately and provide insightful descriptions and analysis of the environment for pBLV.more » « less
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Summary The disproportionate expansion of telencephalic structures during human evolution involved tradeoffs that imposed greater connectivity and metabolic demands on midbrain dopaminergic neurons. Despite the central role of dopaminergic neurons in human-enriched disorders, molecular specializations associated with human-specific features and vulnerabilities of the dopaminergic system remain unexplored. Here, we establish a phylogeny-in-a-dish approach to examine gene regulatory evolution by differentiating pools of human, chimpanzee, orangutan, and macaque pluripotent stem cells into ventral midbrain organoids capable of forming long-range projections, spontaneous activity, and dopamine release. We identify human-specific gene expression changes related to axonal transport of mitochondria and reactive oxygen species buffering and candidatecis-andtrans-regulatory mechanisms underlying gene expression divergence. Our findings are consistent with a model of evolved neuroprotection in response to tradeoffs related to brain expansion and could contribute to the discovery of therapeutic targets and strategies for treating disorders involving the dopaminergic system.more » « less
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